Hormonal mechanisms in breast cancer
digital file Black & White Sound 1974 29:54
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Summary: Patrick Forrest, Regis Professor of Clinical Surgery at the University of Edinburgh talks about breast cancer. A brief summary accompanying the cassette reads: The first demonstration that the endocrine system can influence human breast cancer was in 1896, when Beatson described remission of advanced local disease following oophorectomy. Since then, work both in experimental animals and in man has failed to define precisely the reason for this effect. This programme, which reviews these various studies, includes information on the effect of hormones on the induction and growth of experimental tumours on correlations between curculating hormones and the behaviour of human cancer and on the ways in which the tumour itself can facilitate hormonal action. 5 segments.
Title number: 18365
LSA ID: LSA/21522
Description: Segment 1 Gilliland introduces Forrest. Forrest briefly recaps the history of breast cancer surgery. Time start: 00:00:00:00 Time end: 00:05:49:00 Length: 00:05:49:00 Segment 2 forrest focuses on the kinds of hormones that can cause breast cancer growth. He refers to experiments in which tumours have been artificially grown in mice. Time start: 00:05:49:00 Time end: 00:10:24:00 Length: 00:04:35:00 Segment 3 Forrest shows a diagram detailing the effects of oestrogen on a case of metastatic breast cancer. Time start: 00:10:24:00 Time end: 00:14:37:00 Length: 00:04:13:00 Segment 4 Forrest discusses the correlation between prolactin levels and breast cancer and then the relationship between adrenal steroids and breast cancer. Time start: 00:14:37:00 Time end: 00:21:00:00 Length: 00:06:23:00
Credits: Presented by Professor Patrick Forrest. Introduced by Dr Ian Gilliland. Directed by David Sharp. Produced by Peter Bowen.
Further information: This video is one of more than 120 titles, originally broadcast on Channel 7 of the ILEA closed-circuit television network, given to Wellcome Trust from the University of London Audio-Visual Centre shortly after it closed in the late 1980s. Although some of these programmes might now seem rather out-dated, they probably represent the largest and most diversified body of medical video produced in any British university at this time, and give a comprehensive and fascinating view of the state of medical and surgical research and practice in the 1970s and 1980s, thus constituting a contemporary medical-historical archive of great interest. The lectures mostly take place in a small and intimate studio setting and are often face-to-face. The lecturers use a wide variety of resources to illustrate their points, including film clips, slides, graphs, animated diagrams, charts and tables as well as 3-dimensional models and display boards with movable pieces. Some of the lecturers are telegenic while some are clearly less comfortable about being recorded all are experts in their field and show great enthusiasm to share both the latest research and the historical context of their specialist areas.
Keywords: Breast Neoplasms; Endocrinology; Hormones
Locations: United Kingdom; England; London; University of London
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