The APUD cell series
digital file Black & White Sound 1973 39:52
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Summary: Professor Pearse talks about the APUD cell concept. He explains how APUD cells are a series or collection of endocrine cells which can be found in endocrine glands and other organs all over the body and he describes the history of their discovery, leading up to what is currently known about their function today. 8 segments.
Title number: 18353
LSA ID: LSA/21510
Description: Segment 1 Gilliland introduces Pearse. Pearse begins by explaining what the APUD cell series is and what the initials stand for. He then looks back at this history of the discovery of the theory with particular reference to the work of Fuller Albright. Time start: 00:00:00:00 Time end: 00:05:37:00 Length: 00:05:37:00 Segment 2 Pearse shows slides of enzymes within the pituitary gland and describes some early research into APUD cells located there. Time start: 00:05:37:00 Time end: 00:10:37:14 Length: 00:05:37:14 Segment 3 Pearse refers to tables listing APUD characteristics, then diagrams detailing the most effective methods for demonstrating the presence of APUD cells. Long, detailed tables are shown listing all the different types of APUD cells, 20 in total. A further table lists other cells not yet confirmed as APUD but suspected to be. Time start: 00:10:37:14 Time end: 00:15:15:00 Length: 00:04:37:11 Segment 4 Pearse shows the APUD-FIF technique for labelling cells and describes research into this method. Time start: 00:15:15:00 Time end: 00:21:10:18 Length: 00:05:55:18 Segment 6 Pearse recounts the research of Professor Feyrter into APUD cells. He shows a table which details the Wiesbaden agreement for naming endocrine cells in the stomach and intestine and an illustration of gut endocrine cells. Time start: 00:24:22:00 Time end: 00:29:39:00 Length: 00:05:17:00. Segment 7 Pearse a slide of a television analyser and describes the kind of pictures it makes. Pearse then discusses different types of apudomas, describing them and outlining treatments. Time start: 00:29:39:00 Time end: 00:35:24:00 Length: 00:05:45:00. Segment 8 Pearse looks at the types of cell primarily involved in apudomas. He then summarises and recounts the main points of the lecture. Time start: 00:35:24:00 Time end: 00:39:52:17 Length: 00:04:28:17
Credits: Presented by Professor AG Everson Pearse. Introduced by Dr Ian Gilliland. Produced by Peter Bowen. Made for British Postgraduate Medical Federation.
Further information: This video is one of more than 120 titles, originally broadcast on Channel 7 of the ILEA closed-circuit television network, given to Wellcome Trust from the University of London Audio-Visual Centre shortly after it closed in the late 1980s. Although some of these programmes might now seem rather out-dated, they probably represent the largest and most diversified body of medical video produced in any British university at this time, and give a comprehensive and fascinating view of the state of medical and surgical research and practice in the 1970s and 1980s, thus constituting a contemporary medical-historical archive of great interest.
Keywords: Histochemistry; Endocrinology; APUD Cells; APUD Cells -- physiology
Locations: United Kingdom; England; London; University of London
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