Description: Segment 1 Nunn introduces the lecture and describes how there are different molecular and cellular sites which are affected by inhaled anaesthetic agents. He focuses, in particular, on the effects of anaesthetics on microtubues which he demonstrates on a 3-dimensional model of a microtubule. A short film of the heliozoan Actinosphaerium, a simple pond water creature with notable microtubules, is shown reacting to anaesthetics. The film clip ends. Time start: 00:00:00:00 Time end: 00:05:47:00 Length: 00:05:47:00 Segment 2 Nunn shows a series of electron micrographs of heliozoan Actinosphaerium microtubules and describes their function in detail. He talks about the drug halothane and shows a slide of a broad bean root tip exposed to the drug, then a sea urchin egg before and after exposure to halothane. Nunn introduces Halsey. Time start: 00:05:47:00 Time end: 00:10:55:00 Length: 00:05:08:00 Segment 3 Halsey demonstrates a 3-dimensional model of a haemoglobin molecule. He describes which parts of it are affected by drugs such as halothane. He then shows a diagram detailing the effect of anaesthetics on bioluminescent bacteria in the enzyme system, then a chart showing details of interactions between different types of anaesthesia. Halsey hands back to Nunn. Time start: 00:10:55:00 Time end: 00:16:36:00 Length: 00:05:41:00 Segment 4 Nunn discusses the effects of anaesthesia on motility. He shows a short time-lapse film which shows the effect of anaesthetics on the activity of lymphocytes and narrates over it to explain what is happening. The film clip ends. Time start: 00:16:36:00 Time end: 00:20:11:00 Length: 00:03:35:00 Segment 6 Nunn shows a transverse section of the cilia of a micro-organism after exposure to halothane. He hands over to Halsey. Halsey refers to a diagram showing the effects of anaesthesia on red blood cells. He discusses too the effects of anaesthesia on synaptic transmission. Time start: 00:25:05:11 Time end: 00:30:43:00 Length: 00:05:37:14. Segment 7 Halsey discusses the way in which anaesthetic drugs affect neurotransmitters, referring to detailed diagrams to highlight his points. He hands back to Nunn. Nunn sums up the lecture by saying a proper study of the cellular and molecular effects of anaesthesia should also include studies on the effects of drugs other than inhaled anaesthetics. Time start: 00:30:43:00 Time end: 00:36:58:24 Length: 00:06:15:24