Description: Segment 1 Dr Ian Gilliland introduces Professor Iain Gillespie. Gillespie begins by saying that gastrointestinal hormones have recently 'gained respectability' in the world of endocrinology as previously it was not known that they actually existed. He introduces and describes the three hormones his lecture will feature: gastrin, secretin and cholecystokinin (CCK). Time start: 00:00:00:00 Time end: 00:04:09:00 Length: 00:04:09:00 Segment 2 Gillespie uses a table with moveable pieces to illustrate his points about the structure of the hormone gastrin. He refers then to a graph which shows gastrin levels in different disorders of the stomach. Attention is paid to the vagus nerve and its role in the development of gastric ulcers he describes surgery to remove the vagus (vagotomy) and drugs which suppress its stimulation of gastrin. Time start: 00:04:09:00 Time end: 00:10:45:00 Length: 00:06:39:00 Segment 3 Gillespie shows a graph which measures levels of pentagastrin before and after vagotomy in patients with duodenal ulcers. He them moves on to look at secretions other than acid that are induced by gastrin. He refers to an illustration of the gastrointestinal tract. Time start: 00:10:45:00 Time end: 00:15:44:00 Length: 00:04:59:00 Segment 4 Gillespie moves on to discuss the hormone, secretin. He shows an illustration of its amino acid sequence, then uses graphs and diagrams relating to the effects of secretin on the body. After this, he discusses CCK and its effects on the body, particularly its relationship to smooth muscle tissue. Time start: 00:15:44:00 Time end: 00:20:53:00 Length: 00:05:09:00