Description: Segment 1 Dr Dumonde talks to camera and dramatically introduces the 'field of lymphokines.' He outlines what lymphokines our, pointing out their relation to immunology and delayed allergic hypersensitivity reactions. Dumonde looks back to the 1950s when the major break throughs in lymphokine research occurred he shows photographs of different doctors involved in this research. Time start: 00:05:50:00 Time end: 00:05:50:00 Length: 00:05:50:00 Segment 2 Dumonde continues to look back at the history of lymphokine research. He describes the findings in detail, relating them also to breakthroughs in the medical understanding of the immune system. He shows a slide listing areas for investigation in the field of lymphokines and discusses, in particular, the biochemistry of lymphokines. Time start: 00:05:50:00 Time end: 00:10:00:00 Length: 00:04:10:00 Segment 3 Dumonde shows a photomicrograph demonstrating delayed hypersensitivity in an experiment on a guinea pig. He then discusses the effects of lymphokines on other cells such as macrophages, lymphocytes, polymorphs, fibroblasts and tumour cells. He refers to experiments in which lymphokines have been injected into different organs of the body and their effects on other cells recorded. Time start: 00:10:00:00 Time end: 00:14:33:00 Length: 00:04:33:00 Segment 4 Dumonde refers to slides showing various images of the lymphatic system, which he explains in detail, discussing in particular how lymphokines move around the body and interact with other cells along the way. Time start: 00:14:33:00 Time end: 00:18:18:18 Length: 00:03:45:18 Segment 6 Dumonde shows a photomicrograph of endothelial cells and describes how they can be damaged by lymphokines. He then refers to a diagram showing how the hormone prostaglandin E acts on lymphocytes. Time start: 00:24:28:11 Time end: 00:29:34:00 Length: 00:05:05:14. Segment 7 Dumonde refers to experiments in which lymphokines have been experimentally injected into the ears of guinea pigs. he describes in detail what effect this has on the lymph nodes of the guinea pig. Time start: 00:29:34:00 Time end: 00:35:30:18 Length: 00:05:56:18. Segment 8 Dumonde introduces some of the latest experimental research into lymphokines, particularly with regard to the immune system. He describes different types of allergic reaction and highlights the role of lymphokines in these. Time start: 00:35:30:18 Time end: 00:39:47:00 Length: 00:04:16:07. Segment 9 Dumonde discusses the application of lymphokines to the study of autoimmune disorders. He then refers to how lymphokines can be measured, particularly their biological activity. He describes how bioassays can help in this process and shows a slide of a freeze-dried lymphokine sample. Time start: 00:39:47:00 Time end: 00:44:24:00 Length: 00:04:37:00. Segment 10 Dumonde concludes the lecture by discussing directions in which lymphokine research might go in the future. Time start: 00:44:24:00 Time end: 00:49:56:14 Length: 00:05:22:14